Innate Immunity and Pathology of the Critical patient

Rafael Mañez Mendiluce

PRINCIPAL INVESTIGATORS
  • Joan Sabater Riera
CLINICAL RESEARCHERS
  • Juan Carlos Lopez Delgado
  • Francisco Esteve Urbano
  • Gabriel Jesús Moreno Gonzalez
  • Luisa Corral Ansa
  • Jose Luis Perez Fernandez
COLLABORATORS
  • Salvador Ventura Pedret
PREDOCTORAL RESEARCHERS (R1)
  • Ricard Soley Corderas
  • Sara Olivera Ardid
  • Victor Daniel Gumucio Sanguino
Translational Medicine
Infectious disease and transplantation

Scientific production

15

PAPERS

Impact factor: 77,827

1 PUBLICATION IN FIRST DECILE

8 PUBLICATIONS IN FIRST QUARTILE

10 PUBLICATIONS IN OPEN ACCESS

Selected publications

  • Solanich X, Rigo Bonnin R, Gumucio VD, Bastard P, Rosain J, Philippot Q, Perez Fernandez XL, Fuset Cabanes MP, Gordillo Benitez MÁ, Suarez Cuartin G, Boza Hernandez E, Riera Mestre A, Parra Martínez A, Colobran R, Antolí A, Navarro S, Rocamora Blanch G, Framil M, Calatayud L, Corbella X, Casanova JL, Morandeira F, Sabater Riera J. Pre-existing Autoantibodies Neutralizing High Concentrations of Type I Interferons in Almost 10% of COVID-19 Patients Admitted to Intensive Care in Barcelona. J. Clin. Immunol. 2021;41(8):1-12. doi:10.1007/s10875-021-01136-x. IF:8,32.
  • Solanich X, Vargas Parra G, van der Made CI, Simons A, Schuurs Hoeijmakers J, Antoli A, del Valle J, Rocamora Blanch G, Setien F, Esteller M, van Reijmersdal SV, Riera Mestre A, Sabater Riera J, Capella G, van de Veerdonk FL, van der Hoven B, Corbella X, Hoischen A, Lazaro C. Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19. Front. Immunol. 2021;12doi:10.3389/fimmu.2021.719115. IF:7,56.
  • Peña M, Salas MQ, Mussetti A, Moreno Gonzalez G, Bosch A, Patiño B, Jiménez L, Kara M, Parody R, Sureda A. Pretransplantation EASIX predicts intensive care unit admission in allogeneic hematopoietic cell transplantation. Blood Adv. 2021;5(17):3418-3426. doi:10.1182/bloodadvances.2021004812. IF:6,69.
  • Suarez Cuartin G, Gasa M, Bermudo G, Ruiz Y, Hernandez Argudo M, Marin A, Trias Sabria P, Cordoba A, Cuevas E, Sarasate M, Ariza A, Sabater J, Romero N, Subirana C, Molina M, Santos S. Clinical Outcomes of Severe COVID-19 Patients Admitted to an Intermediate Respiratory Care Unit. Front Med (Lausanne). 2021;8711027-711027. doi:10.3389/fmed.2021.711027. IF:5,09.
  • Anguela Calvet L, Moreno Gonzalez G, Sbraga F, Gonzalez Costello J, Tsui S, Oliver Juan E. Heart Donation From Donors After Controlled Circulatory Death. Transplantation. 2021;105(7):1482-1491. doi:10.1097/TP.0000000000003545. IF:4,94.

Research highlights

PROJECTS

6 Competitive projects
6 Non-competitive project

7 Clinical trials

INNOVATION

1 Patent

1 spin-off 

Selected projects

  • 20CEE013. ENVISION: Intelligent plug-and-play digital tool for real-time surveillance of COVID-19 patients and smart decision-making in Intensive Care Units. (101015930). ACADEMISCH ZIEKENHUIS GRONINGEN; ACCELOPMENT DEUTSCHLAND GMBH; ACCELOPMENT SCHWEIZ AG (ACCELCH); APPATWORK GMBH (AAW); CENTRO HOSPITALAR E UNIVERSITARIO DE COIMBRA E.P.E. (CHUC); COMISSIÓ EUROPEA; DEL-PESTI CENTRUMKORHAZ-ORSZAGOS HEMATOLOGIAI ES INFEKTOLOGIAI INTEZET (DPC); EUROPEAN SOCIETY OF ANAESTHESIOLOGY AISBL (ESA); INSTITUT CATALA DE LA SALUT (ICS); INTELLIGENT DATA ANALYTICS GMBH & CO KG (IDA); JOHANN WOLFGANG GOETHE-UNIVERSITAT FRANKFURT AM MAIN (GUF); LIETUVOS SVEIKATOS MOKSLU UNIVERSITETO LIGONINE KAUNO KLINIKOS (KC); LOWENSTEIN MEDICAL INNOVATION GMBH & CO KG (LMI); SEMMELWEIS EGYETEM UNIVERSITY; SPITALUL CLINIC JUDETEAN DE URGENTA PIUS BRINZEU TIMISOARA (CCHT); TAMPEREEN KORKEAKOULUSAATIO SR; UNIVERSITA DEGLI STUDI DI PERUGIA (UNIPG); UNIVERSITA DEGLI STUDI DI TORINO (UNITO); UNIVERSITATEA DE MEDICINA SI FARMACIE CAROL DAVILA DIN BUCURESTI (UMFCD); UNIVERSITY COLLEGE LONDON; UNIVERZITETNI KLINICNI CENTER LJUBLJANA (UMCL); UNIVERZITETNI KLINICNI CENTER MARIBOR (UMCM). Importe Concedido:115.000,€. 2020-2022. IP:MAÑEZ MENDILUCE,RAFAEL.
  • 20PSJ007. A breakthrough alternative to antibiotics for curing bacterial infectious diseases at Intensive Care Units. (CF91-00005). FUNDACIÓ “LA CAIXA”. Importe Concedido:300.000,€. 2020-2022. IP:MAÑEZ MENDILUCE,RAFAEL.
  • 20DPS003. Elicitation of protective Immunity against SARS-CoV2 by selective Removal of non-neutralizing Antibodies used by the virus to enhance its infectivity (ICoVRA). Importe Concedido:345.254,36€. 2020-2021. IP:MAÑEZ MENDILUCE,RAFAEL.
  • 19AGA006. SeptiLoop (Kit diagnòstic ràpid que identifica les infeccions bacterianes a la sang a través de l’activitat inmune. Aquesta eina de diagnóstic ajuda als metges d’emergencia a prendre millors decisions clíniques i optimizar el maneig de la sèpsia). (2018 PROD 00121). Importe Concedido:98.189,69€. 2019-2021. IP:SABATER RIERA,JOAN.
  • 18FIS024. Papel de los anticuerpos naturales anticarbohidrato en el desarrollo de infecciones nosocomiales por gérmenes gram-negativos multiresistentes. (PI17/01757). ISCIII. Importe Concedido:122.815,€. 2018-2021. IP:MAÑEZ MENDILUCE,RAFAEL.